Three sacred plants. Thousands of years of ceremony.
DYMZ brings together cannabis, Mimosa hostilis and Syrian rue, three plants honored for healing, prayer and protection across four continents. This page shares their stories, with respect and with care.
The plant of the gods · Central Asia, India, Jamaica
Cannabis has been burned in sacred ceremony for at least 2,500 years. Wooden braziers from a tomb high in the Pamir Mountains still held residue of strong cannabis, burned on hot stones during funeral rites around 500 BCE.
In India it is one of five sacred plants in the Atharvaveda and is tied to Lord Shiva. Rastafari came to see ganja as a sacrament that opens reflection.
Believed to: honor the dead, quiet the mind for prayer, and bring people together.
Mimosa hostilis
Jurema preta, the sacred tree · Northeastern Brazil
Indigenous peoples of Brazil's dry backlands made a ceremonial drink, vinho da jurema, from its root bark. It was first written about in the 1700s, and its use is believed to be centuries older.
The ritual survived persecution and lives on in circle dances, chanting and the Afro-Indigenous faith of Catimbó-Jurema, where the tree's roots hold the "cities of jurema," home of the ancestor spirits.
Believed to: heal, reveal, connect people with their ancestors and their land.
Syrian rue
Esfand, the holy seed · Iran, Central Asia, North Africa
Its Persian name comes from the ancient word for "holy." For over a thousand years, families have dropped its seeds on glowing coals to ward off the evil eye at weddings, births and times of illness.
Some scholars believe it was haoma, the sacred drink Zoroastrian priests took to journey into the spirit realm. That theory is still debated.
Believed to: protect, cleanse a space and bring blessing to the home.
A modern story
These three plants were never combined in any ancient tradition. Smoking blends like this are new: the best known, changa, was created in Australia in 2003–2004 and spread through festivals worldwide after 2008.
DYMZ belongs to that young lineage, an old idea of plant partnership in a new form.
Honoring the roots
Jurema is still a sacred practice for Indigenous and Afro-Brazilian communities. Esfand is still burned in homes across Iran. We share their stories with gratitude.
Careless harvesting of mimosa root bark can kill trees and harm the forests where they grow. Choose ethical, sustainable sources that leave trees alive and pay harvesters fairly.
II · CEREMONY
Intention, setting & what comes after
Before
Every tradition treated these plants as ceremony, never as something casual. In that spirit:
Find a quiet, comfortable space and set it with love and intention.
Know what you hope to learn or release.
Have a trusted, sober person with you.
Clear your schedule, and never drive afterward.
After
What happens after the ceremony matters as much as the ceremony. This is called integration.
Rest, and write down what you saw and felt.
Talk it through with someone you trust before making big decisions.
Turn insights into small, practical steps, one habit at a time.
Feeling shaken? The Fireside Project offers free psychedelic support: call or text 62-FIRESIDE (623-473-7433), 11 a.m. to 11 p.m. Pacific.
III · WHAT WE KNOW
What people report, and what research says
People who work with these plants in ceremony often describe a quieter mind, a release of heavy emotions, deep awe and a fresh appreciation for life. Experiences vary widely, and some are difficult or frightening.
Ayahuasca (DMT + MAOI)
In a 2018 trial of 29 people with treatment-resistant depression, one session reduced symptoms more than placebo after a week.
DMT on its own
A 2026 Imperial College London trial of 34 people found one session with therapy beat placebo, with effects lasting up to six months for some.
Cannabis
There is no strong evidence that cannabis treats depression, and heavy use is linked to worse mood for some people.
These studies were small and early, using purified doses given by doctors in clinics. No research has tested a smoked blend like this one. If you are struggling with depression, please talk to a doctor or therapist, or call or text 988.
PLEASE READ
Safety & warnings
Syrian rue is a powerful MAOI. It changes how your body breaks down many medicines and foods, and some combinations can be life-threatening. Speak with your doctor before you approach DYMZ.
Never combine with
SSRIs, SNRIs, MAOIs or other antidepressants. This can cause serotonin syndrome, which can be fatal. Never stop a prescribed medicine without your doctor.
Stimulants, including ADHD medicines, amphetamines, cocaine and MDMA.
Tramadol, dextromethorphan, St. John's wort and some cold and migraine medicines.
Alcohol.
Watch your diet
Foods high in tyramine, such as aged cheese, cured meats, soy sauce and tap beer, can raise blood pressure dangerously while an MAOI is active.
Do not use if you
are pregnant or breastfeeding, have heart problems or high blood pressure, have a personal or family history of psychosis or bipolar disorder, or are under 21.
Call 911 for high fever, heavy sweating, muscle stiffness, a racing heart, chest pain, a sudden severe headache or confusion. The experience can feel intense and very real. You may feel like you've traveled to space. Never use alone.
Glossary
DMT
A naturally occurring psychedelic compound found in Mimosa hostilis root bark.
MAOI
Monoamine oxidase inhibitor: blocks the enzyme that breaks down DMT, certain medicines and some foods.
Beta-carbolines
The alkaloids in Syrian rue, mainly harmine and harmaline, that act as MAOIs.
Entheogen
A plant or substance used in a spiritual or religious setting.
Set and setting
Your mindset going in, and your surroundings. Both shape the experience.
Integration
Reflecting afterward and bringing what you learned into daily life.
Serotonin syndrome
A dangerous reaction to too much serotonin, often from mixing MAOIs with antidepressants.
Tyramine
A compound in aged and fermented foods that can spike blood pressure when an MAOI is active.